128134-30-5

Basic information

• Product Name: (R)-4-(2-Carboxy-cyclopropyl)-5-oxo-oxazolidine-3-carboxylic acid benzyl ester
• CAS NO: 128134-30-5
• Molecular Weight: 305.287
• Mol File: 128134-30-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-4-(2-Carboxy-cyclopropyl)-5-oxo-oxazolidine-3-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-(2-Carboxy-cyclopropyl)-5-oxo-oxazolidine-3-carboxylic acid benzyl ester(128134-30-5)
• EPA Substance Registry System: (R)-4-(2-Carboxy-cyclopropyl)-5-oxo-oxazolidine-3-carboxylic acid benzyl ester(128134-30-5)

Safety Data

• Hazardous Substances Data: 128134-30-5(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 22255-17-0 2-((R)-Amino-carboxy-methyl)-cyclopropanecarboxylic acid 
• 501-53-1 benzyl chloroformate 
• 128134-29-2 2-((R)-Benzyloxycarbonylamino-methoxycarbonyl-methyl)-cyclopropanecarboxylic acid ethyl ester 

Downstream Products

• 22255-17-0 (2R,3S,4S) α-(Carboxycyclopropyl)glycine 
• 22255-17-0 (2R,3R,4R) α-(Carboxycyclopropyl)glycine 
• 128134-31-6 (R)-4-[(S)-2-((R)-2-Hydroxy-1-phenyl-ethylcarbamoyl)-cyclopropyl]-5-oxo-oxazolidine-3-carboxylic acid benzyl ester 
• 128134-31-6 (R)-4-[(R)-2-((R)-2-Hydroxy-1-phenyl-ethylcarbamoyl)-cyclopropyl]-5-oxo-oxazolidine-3-carboxylic acid benzyl ester 

Relevant articles and documents

D-3,4-'cyclopropylglutamate' isomers as nmda receptor ligands: Synthesis and enantioselective activity

Dirhodium(II) tetraacetate catalyzed decomposition of ethyl diazoacetate in the presence of D-Cbz-vinylglycine methyl ester (11) afforded a mixture of the cyclopropyl esters D-CGA A-D (13) from which the corresponding 2R-acids 7-10 were obtained and their absolute configurations assigned. The (2R,3S,4R) α-(carboxycyclopropyl)glycine (D-CGA C, 9 resulted to be the most potent and selective among the NMDA receptor ligands yet reported.