128156-55-8Relevant academic research and scientific papers
Novel synthesis of benzoxazoles from o-nitrophenols and amines
Nishioka, Hiromi,Ohmori, Yukiko,Iba, Yumiko,Tsuda, Eri,Harayama, Takashi
, p. 193 - 198 (2004)
o-Nitrophenols and o-nitroaniline were reacted with amines at 210-215°C to produce the corresponding benzoxazoles and benzimidazoles, respectively, in moderate yields. The reactions between o-nitrophenols containing a CO2Me or OMe group on their benzene rings and N,N-diethylaniline were examined to investigate the effects of the position and electronic character of these substituents on the formation of the oxazole ring.
