128176-35-2Relevant academic research and scientific papers
The effect of propargyl oxygen substituents in the carbene-chromium/alkyne cycloaddition
Semmelhack,Jeong,Lee
, p. 609 - 610 (2007/10/02)
The usual reaction of alkynes with arylcarbene chromium complexes is deflected by the presence of propargylic alkoxy groups, especially in the case of the 2,5-dimethoxyphenyl carbene ligand; indenes and furans become significant products.
Approach to the synthesis of nogalarol via the cycloaddition of a carbene-chromium complex with a functionalized alkyne
Semmelhack,Jeong, Nakcheol
, p. 605 - 608 (2007/10/02)
The alkyne, 4, prepared stereoselectively in 7 steps from acetyl furan, reacts with (methoxy)(phenyl)carbenepentacarbonylchromium(0), 15, to give the model (16) for nogalarol (1b) in 43% yield.
