1281870-42-5
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Basic information
- Product Name: Rhosin (hydrochloride)
- Synonyms: Rhosin (hydrochloride);Rhosin HCl;(R,E)-2-amino-3-(1H-indol-3-yl)-N'-(quinoxalin-6-ylmethylene)propanehydrazide hydrochloride
- CAS NO:1281870-42-5
- Molecular Formula: C20H19ClN6O
- Molecular Weight: 394.85746
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1281870-42-5.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Rhosin (hydrochloride)(CAS DataBase Reference)
- NIST Chemistry Reference: Rhosin (hydrochloride)(1281870-42-5)
- EPA Substance Registry System: Rhosin (hydrochloride)(1281870-42-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1281870-42-5(Hazardous Substances Data)
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1281870-42-5 Usage
Description
Rhosin (hydrochloride), also known as the hydrochloride salt of rhosin, is a D-tryptophan derivative with the chemical abstracts service number 1173671-63-0. It functions as an inhibitor of Rho GTPases, which are proteins involved in various cellular processes. Rhosin (hydrochloride) holds potential in the medical field, particularly for its application in reversing chemotherapy resistance in diffuse-type gastric adenocarcinoma.Uses
Used in Oncology:Rhosin (hydrochloride) is utilized as a therapeutic agent in oncology for its potential to reverse chemotherapy resistance in diffuse-type gastric adenocarcinoma. By inhibiting Rho GTPases, it may help overcome the challenges faced by patients with this type of cancer, improving the effectiveness of chemotherapy treatments.
Used in Pharmaceutical Research:
In the pharmaceutical industry, Rhosin (hydrochloride) serves as a valuable compound for research and development. Its role as an inhibitor of Rho GTPases makes it a candidate for the creation of new drugs targeting various diseases where these proteins play a significant role. This includes not only cancer but potentially other conditions influenced by Rho GTPase activity.
Check Digit Verification of cas no
The CAS Registry Mumber 1281870-42-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,8,1,8,7 and 0 respectively; the second part has 2 digits, 4 and 2 respectively.Calculate Digit Verification of CAS Registry Number 1281870-42:
(9*1)+(8*2)+(7*8)+(6*1)+(5*8)+(4*7)+(3*0)+(2*4)+(1*2)=165
165 % 10 = 5
So 1281870-42-5 is a valid CAS Registry Number.
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Rhosin (hydrochloride)
