1282061-37-3Relevant academic research and scientific papers
Cooperative activation with chiral nucleophilic catalysts and n-haloimides: Enantioselective iodolactonization of 4-arylmethyl-4-pentenoic acids
Nakatsuji, Hidefumi,Sawamura, Yasuhiro,Sakakura, Akira,Ishihara, Kazuaki
, p. 6974 - 6977 (2014/07/08)
Chiral triaryl phosphates promote the enantioselective iodolactonization of 4-substituted 4-pentenoic acids to give the corresponding iodolactones in high yields with high enantioselectivity. N-Chlorophthalimide (NCP) is employed as a Lewis acidic activat
Pd(II)-catalyzed intramolecular amidoarylation of alkenes with molecular oxygen as sole oxidant
Yip, Kai-Tai,Yang, Dan
supporting information; experimental part, p. 2134 - 2137 (2011/06/19)
Stereoselective palladium-catalyzed synthesis of structurally versatile indoline derivatives, using molecular oxygen as the sole oxidant, is described. New C-N and C-C bonds form across an alkene in an intramolecular manner. The C-N bond-forming step proceeds via a syn-amidopalladation pathway. The moderate kinetic isotope effects (intramolecular KIE = 3.56) suggest that electrophilic aromatic substitution occurs in the arylation step.
