1282468-36-3Relevant academic research and scientific papers
Synthesis and structure-activity relationship of aminopyridines with substituted benzoxazoles as c-Met kinase inhibitors
Lee, Jongkook,Han, Sun-Young,Jung, Heejung,Yang, Jeon,Choi, Jie-Won,Chae, Chong Hack,Park, Chi Hoon,Choi, Sang Un,Lee, Kwangho,Ha, Jae Du,Lee, Chong Ock,Ryu, Jae Wook,Kim, Hyoung Rae,Koh, Jong Sung,Cho, Sung Yun
scheme or table, p. 4044 - 4048 (2012/07/03)
A series of hydroxybenzoxazole derivatives was synthesized, and their c-Met kinase inhibitory activity was evaluated. Described herein is a potent c-Met inhibitor by structural modification of the parent benzoxazole scaffold, with particular focus on the hydroxyl substituent of the benzoxazole moiety.
