1282514-51-5

Basic information

• Product Name: (S)-1-(2-(3-Methyl-1-(2,2,2-trifluoroethyl)-1H-1,2,4-triazol-5-yl)-5,6-dihydroiMidazo[1,2-d]pyrido[3,4-f][1,4]oxazepin-9-yl)pyrrolidine-2-carboxaMide
• Synonyms: (S)-1-(2-(3-Methyl-1-(2,2,2-trifluoroethyl)-1H-1,2,4-triazol-5-yl)-5,6-dihydroiMidazo[1,2-d]pyrido[3,4-f][1,4]oxazepin-9-yl)pyrrolidine-2-carboxaMide;(S)-1-(2-(3-Methyl-1-(2,2,2-trifluoroethyl)-1H-1,2,4-triazol-5-yl)-5,6-dihydroiMidazo[1,2-d]pyrido[3,4-f][1,4]oxazepin-9-
• CAS NO: 1282514-51-5
• Molecular Formula: C20H21F3N8O2
• Molecular Weight: 462.4283496
• EINECS: -0
• Mol File: 1282514-51-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-1-(2-(3-Methyl-1-(2,2,2-trifluoroethyl)-1H-1,2,4-triazol-5-yl)-5,6-dihydroiMidazo[1,2-d]pyrido[3,4-f][1,4]oxazepin-9-yl)pyrrolidine-2-carboxaMide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(2-(3-Methyl-1-(2,2,2-trifluoroethyl)-1H-1,2,4-triazol-5-yl)-5,6-dihydroiMidazo[1,2-d]pyrido[3,4-f][1,4]oxazepin-9-yl)pyrrolidine-2-carboxaMide(1282514-51-5)
• EPA Substance Registry System: (S)-1-(2-(3-Methyl-1-(2,2,2-trifluoroethyl)-1H-1,2,4-triazol-5-yl)-5,6-dihydroiMidazo[1,2-d]pyrido[3,4-f][1,4]oxazepin-9-yl)pyrrolidine-2-carboxaMide(1282514-51-5)

Safety Data

• Hazardous Substances Data: 1282514-51-5(Hazardous Substances Data)

Relevant articles and documents

BENZOXAZEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE

Benzoxazepin compounds of Formula I, including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, wherein: Z1 is CR1 or N; Z2 is CR2 or N; Z3 is CR3 or N; Z4 is CR4 or N; and B is a pyrazolyl, imidazolyl, or triazolyl ring fused to the benzoxepin ring, are useful for inhibiting lipid kinases including p110 alpha and other isoforms of PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.