128252-45-9Relevant academic research and scientific papers
Formation of Complex Hydrazine Derivatives via Aza-Lossen Rearrangement
Polat, Dilan E.,Brzezinski, David D.,Beauchemin, André M.
supporting information, p. 4849 - 4852 (2019/06/27)
The development of a broadly applicable procedure for the aza-Lossen rearrangement is reported. This process converts amines into complex hydrazine derivatives in two steps under safe, mild conditions. This method allows the chemoselective formation of N-
Asymmetric Diels-Alder Cycloadditions with Chiral Carbamoyl Dienophiles
Defoin, Albert,Brouillard-Poichet, Agnes,Streith, Jacques
, p. 109 - 123 (2007/10/02)
Chiral acylnitroso dienophiles 14, which were obtained from L-proline and from D-mandelic acid, reacted with cyclohexa-1,3-diene to give the expected diastereoisomers 15 and 16 (Scheme 2 and Table 1).The d.e. values for these Diels-Alder reactions were moderate; they are related to the molecular stiffness of the dienophiles.The absolute configuration of the major cycloadducts was interpreted in terms of HOMO/LUMO interactions, the approach being 'endo' and the acylnitroso dienophiles reacting from their s-cis-conformation.
Asymmetric Diels-Alder cycloadditions with acylnitroso dienophiles obtained from L-proline
Brouillard-Poichet,Defoin,Streith
, p. 7061 - 7064 (2007/10/02)
N-acylnitroso derivatives of L-proline were formed in situ from the corresponding hydroxamic acids. They reacted easily with 1,3-cyclohexadiene to give the corresponding diastereoisomeric pairs of Diels-Alder cycloadducts with d.e. values ranging from 52 to 68%.
