1282550-76-8

Basic information

• Product Name: ethyl 2-[4-(4-ethoxy-2-fluorophenyl)-10,10-dimethyl-3-oxo-2-(3-phenylpropyl)-5,7-dioxa-2-aza-10-silaundec-1-yl]-5-methyl-1,3-thiazole-4-carboxylate
• Synonyms: ethyl 2-[4-(4-ethoxy-2-fluorophenyl)-10,10-dimethyl-3-oxo-2-(3-phenylpropyl)-5,7-dioxa-2-aza-10-silaundec-1-yl]-5-methyl-1,3-thiazole-4-carboxylate
• CAS NO: 1282550-76-8
• Molecular Weight: 644.88
• Mol File: 1282550-76-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2-[4-(4-ethoxy-2-fluorophenyl)-10,10-dimethyl-3-oxo-2-(3-phenylpropyl)-5,7-dioxa-2-aza-10-silaundec-1-yl]-5-methyl-1,3-thiazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-[4-(4-ethoxy-2-fluorophenyl)-10,10-dimethyl-3-oxo-2-(3-phenylpropyl)-5,7-dioxa-2-aza-10-silaundec-1-yl]-5-methyl-1,3-thiazole-4-carboxylate(1282550-76-8)
• EPA Substance Registry System: ethyl 2-[4-(4-ethoxy-2-fluorophenyl)-10,10-dimethyl-3-oxo-2-(3-phenylpropyl)-5,7-dioxa-2-aza-10-silaundec-1-yl]-5-methyl-1,3-thiazole-4-carboxylate(1282550-76-8)

Safety Data

• Hazardous Substances Data: 1282550-76-8(Hazardous Substances Data)

Upstream product

• 57332-84-0 3-bromo-2-oxo-butyric acid ethyl ester 
• 1282549-65-8 ethyl 2-formyl-5-methyl-1,3-thiazole-4-carboxylate 
• 1282549-69-2 ethyl 2-(diethoxymethyl)-5-methyl-1,3-thiazole-4-carboxylate 
• 1282549-74-9 ethyl 5-methyl-2-{[(3-phenylpropyl)amino]methyl}-1,3-thiazole-4-carboxylate 
• 1282550-73-5 (4-ethoxy-2-fluorophenyl){[2-(trimethylsilyl)ethoxy]methoxy}acetic acid 

Downstream Products

• 1282550-08-6 2-[4-(4-ethoxy-2-fluorophenyl)-10,10-dimethyl-3-oxo-2-(3-phenylpropyl)-5,7-dioxa-2-aza-10-silaundec-1-yl]-5-methyl-1,3-thiazole-4-carboxylic acid 

Relevant articles and documents

SUBSTITUTED AMIDE COMPOUND

[Problem] The present invention provides a substituted amide compound, such as a compound represented by the following structural formula, and the like, which is useful as an active ingredient of a pharmaceutical composition, in particular, a pharmaceutical composition for treating diseases caused by lysophosphatidic acid (LPA). [Means for Solving the Problem] The present inventors have made intensive studies on a compound having an antagonistic action against LPA receptor, and as a result, they have found that a substituted amide compound which is the compound of the present invention has an excellent antagonistic action against LPA receptor and is useful as an agent for preventing and/or treating diseases caused by LPA, thereby completing the present invention.