128256-54-2

Upstream product

• 128256-50-8 3-methyl-1-phenyl-4-acetyl-2-pyrazoline-5-thione 
• 128256-48-4 3-methyl-1-phenyl-4-iminoacetyl-2-pyrazolin-5-thione 
• 128256-47-3 4-(1-iminoethyl)-3-methyl-1-phenyl-2-pyrazolin-5-one 

Downstream Products

• 128256-57-5 3(α-hydroxymethylene-α-formylmethyl)-1-phenyl-4-chloroacetylidene-2-pyrazolin-5-thione 
• 128256-74-6 3-(4isoxazyl)-1-phenyl-4-chloroacetylidene-2-pyrazolin-5-thione 
• 128256-63-3 3-(α-piperidinomethylene-α-formylmethyl)-1-phenyl-4-chloroacetylidene-2-pyrazolin-5-thione 
• 128256-64-4 3-(α-morpholinomethylene-α-formylmethyl)-1-phenyl-4-chloroacetylidene-2-pyrazolin-5-thione 
• 128256-65-5 3-(α-piperazinomethylene-α-formylmethyl)-1-phenyl-4-chloroacetylidene-2-pyrazolin-5-thione 
• 128256-53-1 3(α-dimethylaminomethylene-α-formylmethyl)-1-phenyl-4-chloroacetylidene-2-pyrazolin-5-thione 

Relevant academic research and scientific papers

STUDIES ON THE VILSMEIER-HAACK REACTION. PART IV. SYNTHESIS AND REACTION OF SOME 3-METHYL-1-PHENYL-4-(ACETYL; IMINOACETYL AND THIOACETYL)-2-PYRAZOLIN-5-THIONE

Three derivatives of 5-thiopyrazolone (3-5) have been synthesized.The 3-methyl group in each of these derivatives has been found to undergo diformylation by Vilsmeier reagent to give the corresponding aminoacroleins (6-8).Treatment of 6-8 with some reagents affords the related thiopyrazolone derivatives (12-29) with different heterocyclic systems at the 3-position.