128259-86-9Relevant academic research and scientific papers
Halofluorination of Alkenes Using Dilute Hydrofluoric Acid
Kuroboshi, Manabu,Hiyama, Tamejiro
, p. 1799 - 1806 (2007/10/03)
Iodofluorination of alkenes was achieved with N-iodosuccinimide, potassium hydrogendifluoride, and 1 M hydrofluoric acid using tetrabutylammonium fluoride as a phase-transfer catalyst.The active fluorinating reagent was shown to be tetrabutylammonium dihy
Halofluorination of Alkenes Using Tetrabutylammonium Dihydrogentrifluoride
Kuroboshi, Manabu,Hiyama, Tamejiro
, p. 1215 - 1218 (2007/10/02)
Regio-, stereo-, and chemoselective halofluorination of alkenes is achieved using N-haloamides and tetrabutylammonium dihydrogentrifluoride, and the resulting F-I adducts were successfully converted into fluoroalkenes under dehydroiodation with 1,8-diazab
PHARMACEUTICALLY ACTIVE 3-HETEROARYL-2-FLUORO-1-OLEFINS
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, (2008/06/13)
This invention relates to novel 3-heteroaryl-2-fluoro-l-olefins and their pharmacological use as dopamine beta-hydroxylase DBH inhibitors in the treatment of DBH mediated conditions such as hypertension.
Novel process for the synthesis of 2-fluoro-1-olefins
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, (2008/06/13)
A process for preparing 2-fluoro-1-olefins or terminal bis-beta-fluoro-olefins which comprises reacting an appropriate allyl or alpha-olefinated starting material with phenylselenyl chloride and silver fluoride, and then reacting the intermediate phenylselenyl fluoride compound with ozone, and further reacting the resulting phenylselenoxide compound with an appropriate amine, to yield the desired fluorinated compounds.
A new synthesis of 2-fluoro-1-olefins
McCarthy, James R.,Matthews, Donald P.,Barney, Charlotte L.
, p. 973 - 976 (2007/10/02)
The first examples of the addition of PhSeF to olefins to yield β-fluoro phenylselenides (2) are reported. β-Fluoro phenylselenides (2) obtained from terminal olefins were converted to the title vinyl fluorides 3 on treatment with ozone, whereas, 2 obtain
