128259-95-0

Upstream product

• 79-24-3 Nitroethane 
• 5650-07-7 3-methyl-1-phenyl-but-2-en-1-one 
• 128260-03-7 4,4-ethylenedioxy-2-methyl-4-phenylbutan-2-ol 
• 124286-37-9 3-methyl-3-nitro-1-phenylbutan-1-one 

Downstream Products

• 110466-47-2 3,3-trimethyl-2-methylidene-5-phenyl-3,4-dihydro-2H-pyrrole 
• 110466-46-1 2,3,3-trimethyl-5-phenyl-3H-pyrrole 
• 110466-45-0 2-hydroxy-2,3,3-trimethyl-5-phenyl-3,4-dihydro-2 H-pyrrole 
• 110466-44-9 2-hydroxy-4,4,5-trimethyl-2-phenyl-3,4-dihydro-2 H-pyrrole 
• 110466-43-8 3,3-dimethyl-1-phenylpentane-1,4-dione 

Relevant academic research and scientific papers

Synthesis of β-nitro ketones from geminal bromonitroalkanes and silyl enol ethers by visible light photoredox catalysis

Various β-nitro ketones, including those bearing a β-tertiary carbon, were prepared from geminal bromonitroalkanes and trimethylsilyl enol ethers of a broad range of ketones by visible light photoredox catalysis, which were then easily converted into β-amino ketones, 1,3-amino alcohols, α,β-unsaturated ketones, β-cyano ketones and γ-nitro ketones.

Synthesis and Chemistry of Azolenines. Part 16. Preparation of both 3H- and 2H-Pyrroles from 2,2-Disubstituted 1,4-Diketones via the Paal-Knorr Reaction, and Isolation of Intermediate 2-Hydroxy-3,4-dihydro-2H-pyrroles

Treatment of 2,2-disubstituted 1,4-diketones (1) with liquid ammonia gives high yields of isolable isomeric 2-hydroxy-3,4-dihydro-2H-pyrroles (10) and (11), many of which may be dehydrated to 3H-pyrroles (2) together, in certain cases, with isomeric methylene-pyrrolines (14) and (15).When heated in acetic acid with ammonium acetate, the diketones (1) yield 2H-pyrroles (18), sometimes in admixture with 3H-pyrroles (2) from which they are formed by rearrangement.The diketones (1), including some novel examples, are prepared from nitro-ketones (6) by the Nef reaction, as well as other methods.