128264-02-8Relevant academic research and scientific papers
Derivatized alkanolamines as cardiovascular agents
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, (2008/06/13)
Novel derivatized alkanolamines of the following structural formula STR1 are described as useful cardiovascular agents. Most especially described is their usefulness as cardiovascular agents exhibiting an antiarrhythmic effect. Said antiarrhythmic effect is of a combination Class II/Class III variety. Pharmaceutical formulations containing such compounds are also described.
Synthesis of novel (aryloxy)propanolamines and related compounds possessing both class II and class III antiarrhythmic activity
Lis,Morgan Jr.,Marisca,Gomez,Lind,Davey,Phillips,Sullivan
, p. 2883 - 2891 (2007/10/02)
Several (aryloxy)propanolamines and related compounds (i.e. 5-13, 16-18, 20-24, 27-33, 35, 37-39, 41, and 42) were synthesized and investigated for their class III electrophysiological activity and class II (β-blocking) effects with use of in vitro and in
