128271-46-5Relevant academic research and scientific papers
Manganese-Catalyzed Aerobic Oxytrifluoromethylation of Styrene Derivatives Using CF3SO2Na as the Trifluoromethyl Source
Yang, Yi,Liu, Yingle,Jiang, Yan,Zhang, Yu,Vicic, David A.
, p. 6639 - 6648 (2015/10/06)
A mild and practical protocol for manganese-catalyzed aerobic oxytrifluoromethylation of olefinic bonds of styrene derivatives using CF3SO2Na (Langlois reagent) as the CF3 source is described. A distinguishing feature of this method is the generation of trifluoromethyl radicals from CF3SO2Na using the simple manganese salt/O2 system. The reaction proceeds under ambient conditions, free of added peroxide initiators, and provides moderate to good selectivities for alcohol versus ketone product.
Three-component oxytrifluoromethylation of alkenes: Highly efficient and regioselective difunctionalization of C=C bonds mediated by photoredox catalysts
Yasu, Yusuke,Koike, Takashi,Akita, Munetaka
supporting information, p. 9567 - 9571 (2012/11/07)
Here comes the sun: A facile vicinal difunctionalization of alkenes, oxytrifluoromethylation, was established by visible-light-driven photoredox catalysis. Judicious choice of the CF3 source is key. Nucleophiles such as water, alcohols, and carboxylic acids can be used in this highly efficient (2-4 h) and regioselective (100 %) transformation using light-emitting diode (LED) lamps and natural sunlight. SET=single-electron transfer. Copyright
In situ generation of 3,3,3-trifluoropropanal and its use for carbon-carbon bond-forming reactions
Yamazaki, Takashi,Kobayashi, Rei,Kitazume, Tomoya,Kubota, Toshio
, p. 2499 - 2502 (2007/10/03)
The DIBAL reduction of 2-phenylethyl 3,3,3-trifluoro-2-methylpropionate 2 at -78 °C afforded the aluminum acetal 3, and this intermediate, on worming up to 0 °C, was found to slowly decompose into the corresponding aldehyde 4, which smoothly reacted with
