128273-52-9Relevant academic research and scientific papers
Discovery of Inhibitor of Wnt Production 2 (IWP-2) and Related Compounds As Selective ATP-Competitive Inhibitors of Casein Kinase 1 (CK1) δ/?
García-Reyes, Balbina,Witt, Lydia,Jansen, Bj?rn,Karasu, Ebru,Gehring, Tanja,Leban, Johann,Henne-Bruns, Doris,Pichlo, Christian,Brunstein, Elena,Baumann, Ulrich,Wesseler, Fabian,Rathmer, Bernd,Schade, Dennis,Peifer, Christian,Knippschild, Uwe
supporting information, p. 4087 - 4102 (2018/05/23)
Inhibitors of Wnt production (IWPs) are known antagonists of the Wnt pathway, targeting the membrane-bound O-acyltransferase porcupine (Porcn) and thus preventing a crucial Wnt ligand palmitoylation. Since IWPs show structural similarities to benzimidazol
Novel derivatives of benzimidazole and imidazo-pyridine and their use as medicaments
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Page/Page column 12-14, (2008/06/13)
A compound of the formula wherein the substituents are as defined in the specification and pharmaceutical salts thereof having a good affinity for sub-types of melanocortin receptors making them useful for treating diseases in which such receptors are included such as pain, inflammatory conditions, etc.
Thiadiazines, and insecticidal and acaricidal preparations
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, (2008/06/13)
Novel tetrahydro-1,3,5-thiadiazin-4-ones of the following general formula (I) or their salts which are useful as an insecticidal and acaricidal agent. STR1 In the formula, each of R1 and R2 represents a halogen atom or a C1/sub
