128277-04-3

Basic information

• Product Name: 4-Amino-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester
• CAS NO: 128277-04-3
• Molecular Weight: 277.347
• Mol File: 128277-04-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Amino-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester(128277-04-3)
• EPA Substance Registry System: 4-Amino-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester(128277-04-3)

Safety Data

• Hazardous Substances Data: 128277-04-3(Hazardous Substances Data)

Upstream product

• 4651-91-6 3-cyano-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene 
• 623-49-4 ethyl cyanoformate 

Relevant articles and documents

Reaction of Nitriles under Acidic Conditions. Part VI. Synthesis of Condensed 4-Chloro- and 4-Aminopyrimidines from ortho-Aminonitriles

Condensation of a nitrile with benzene, furan and thiophene ortho-aminonitriles in the presence of dry hydrogen chloride yields condensed 4-chloropyrimidines, condensed 4-aminopyrimidines or a mixture of the two condensed pyrimidines in varying proportions depending upon the nature of the nitrile and the substrate, ortho-aminonitrile.