128307-90-4

Usage

Function

Analgesic and antipyretic drug

Purpose

Relieve mild to moderate pain and reduce fever

Mechanism of action

Inhibits the production of prostaglandins involved in inflammation and pain

Structural similarity

Other nonsteroidal anti-inflammatory drugs (NSAIDs)

Common combinations

Paracetamol and caffeine

Dosage forms

Tablets, capsules, and injections

Typical uses

Treating headaches, menstrual pain, and musculoskeletal pain

Precautions

Potential for causing adverse effects such as gastrointestinal irritation and kidney damage; use with caution and under supervision of a healthcare professional

Upstream product

• 74378-55-5 o-hydroxyacetophenone-isopropylimine 
• 74378-55-5 2-(1-isopropyliminoethyl) phenol 
• 118-93-4 o-hydroxyacetophenone 

Relevant academic research and scientific papers

Ready N-alkylation of enantiopure aminophenols: Synthesis of tertiary aminophenols

A regioselective indirect alkylation of aminophenols to enantiopure tertiary aminophenols, which are useful chiral ligands for metal-catalysed asymmetric reactions, is reported. This very simple synthetic methodology, through reduction or alkylation of an intermediate benzoxazine, was performed in mild conditions, suitable for the conservation of the configuration of the stereogenic centres. Some crystalline aminophenols show the phenomenon of 'crystallization-induced asymmetric transformation'.

Syntheses d'aminoalcools-1,3 ou d'aminophenols-1,3 par reduction d'enaminones ou d'iminophenols par les hydrures metalliques. Etude structurale par infrarouge et RMN des aminoalcools-1,3 bisecondaires diastereomeres

Enaminones, obtained by reaction of a primary amine with a β-diketone, can take three tautomeric forms: keto-enamine Ia, keto-imine Ib and imino-enol Ic.In general the keto-enamine form Ia is the most stable.Thi