1283097-03-9Relevant academic research and scientific papers
Synthesis,11B- and19F NMR spectroscopy, and optical and electrochemical properties of novel 9-aryl-3-(aryl/heteroaryl)-1,1-difluoro-7-(trifluoromethyl)-1H-[1,3,5,2]oxadiazaborinino[3,4-a][1,8]naphthyridin-11-ium-1-uide complexes
Bonacorso, Helio G.,Calheiro, Tainara P.,Iglesias, Bernardo A.,Berni, Iuri R.C.,da Silva Júnior, Eufranio N.,Rocha, Jo?o B.T.,Zanatta, Nilo,Martins, Marcos A.P.
, p. 5017 - 5021 (2016/11/09)
A new series of nine examples of 9-aryl-3-(aryl/heteroaryl)-1,1-difluoro-7-(trifluoromethyl)-1H-[1,3,5,2]oxadiazaborinino[3,4-a][1,8]naphthyridin-11-ium-1-uides, which contained 1,8-naphthyridine-based boron complexes with variable ligand structures, were synthesized at yields of 50–65% from the reaction of unpublished 2-benzoylamino-7-aryl(heteroaryl)-5-trifluoromethyl-1,8-naphthyridines—in which aryl(heteroaryl) = phenyl, 4-MeC6H4, 4-FC6H4, 4-BrC6H4, 4-OMeC6H4, 4-NO2C6H4, and 2-thienyl—with BF3·Et2O and fully characterized by1H-,13C-,19F-, and11B NMR spectroscopy and X-ray diffractometry. The optical and electrochemical properties of the new complexes were investigated, and the results for quantum yield calculations, Stokes shift, UV–vis, fluorescence, and redox potential data analysis indicated an important relationship with the aryl(heteroaryl) substituents attached to the 3- and 9-position of the naphthyridine boron complexes.
General pathway for a convenient one-pot synthesis of trifluoromethyl- containing 2-amino-7-alkyl(aryl/heteroaryl)- 1,8-naphthyridines and fused cycloalkane analogues
Bonacorso, Helio G.,Andrighetto, Rosalia,Krueger, Nicolas,Zanatta, Nilo,Martins, Marcos A.P.
, p. 2817 - 2832 (2011/05/30)
A convenient and general method for the synthesis in 26-73% yields of a new series of 7-alkyl(aryl/heteroaryl)-2-amino-5-trifluoromethyl-1,8-naphthyridines from direct cyclocondensation reactions of 4-alkoxy-1,1,1-trifluoroalk-3-en-2- ones [CF3
