128312-11-8

Basic information

• Product Name: 3-(Methylthio)phenylboronic acid
• Synonyms: 3-(Methylthio)phenyl;3-(Methylthio)phenylboronic Acid 3-(Methylsulphanyl)benzeneboronic acid, 3-Boronophenyl methyl sulphide;3-THIOANISOLEBORONIC ACID;(3-THIOMETHYLPHENYL)BORONIC ACID;3-(METHTHIO)PHENYLBORONIC ACID;3-(METHYLSULFANYL)PHENYLBORONIC ACID;3-(METHYLTHIO)BENZENEBORONIC ACID
• CAS NO: 128312-11-8
• Molecular Formula: C₇H₉BO₂S
• Molecular Weight: 168.02
• EINECS: 1533716-785-6
• Product Categories: Boronate Ester;Potassium Trifluoroborate;Others;blocks;BoronicAcids;Boronic acids;Boronic Acid;Aryl;Organoborons;B (Classes of Boron Compounds);Boronic Acids;Boronic Acids and Derivatives
• Mol File: 128312-11-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 160-162 °C(lit.)
• Boiling Point: 210-215C
• Flash Point: 160.9 °C
• Appearance: white crystalline powder
• Density: 1,087g/cm
• Vapor Pressure: 1.77E-08mmHg at 25°C
• Refractive Index: 1,423-1,425
• Storage Temp.: Keep Cold
• Solubility: soluble in Methanol
• BRN: 7020728
• CAS DataBase Reference: 3-(Methylthio)phenylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Methylthio)phenylboronic acid(128312-11-8)
• EPA Substance Registry System: 3-(Methylthio)phenylboronic acid(128312-11-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26-36-7/9-24/25
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 128312-11-8(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline powder

Uses

suzuki reaction

InChI:InChI=1/C7H9BO3S/c9-8(10)5-11-6-2-1-3-7(12)4-6/h1-2,4,9-10H,3,5H2

Upstream product

• 121-43-7 Trimethyl borate 

Downstream Products

• 10075-91-9 3,3'-di(methylthio)biphenyl 
• 1005201-34-2 2-methyl-5-{3-[3-(methylsulfanyl)phenyl]-1-benzofuran-5-yl}-1,3,4-oxadiazole 
• 1198421-55-4 (6S)-6-{[3'-(methylsulfanyl)[1,1'-biphenyl]-2-yl]methoxy}-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine 
• 100-68-5 methyl-phenyl-thioether 
• 31477-46-0 3-methylsulfanylbiphenyl 
• 884844-91-1 2-(4-methylthiophenyl)-4-(2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-henicosafluorodecyl)-[1,3,2]dioxaborolane 
• 160775-68-8 2,2-Dimethoxy-5-(3-methylsulfanyl-phenyl)-indan-1,3-dione 
• 1320208-26-1 (R)-1,1,1-trifluoro-2-(3-(methylthio)phenyl)propan-2-ol 
• 1320208-25-0 (S)-2-(3-(methylthio)phenyl)-2-(trifluoromethyl)oxirane 

Relevant articles and documents

Hydroxamic acid derivatives as matrix metalloprotease (MMP) inhibitors

Compounds of formula (I):or pharmaceutically or veterinarily acceptable salts thereof, or pharmaceutically or veterinarily acceptable solvates of either entity, wherein the broken line represents an optional bond; A is C or CH; B is CH2, O or absent; R1 and R2 are each independently selected from hydrogen, C1 to C6 alkyl optionally substituted with C1 to C4 alkoxy or phenyl, and C1 to C6 alkenyl; or, together with the carbon atom to which they are attached, form a C3 to C6 cycloalkyl group which optionally incorporates a heteroatom linkage selected from O, SO, SO2 and NR6 or which is optionally benzo-fused; R3 is hydrogen, halo, R7 or OR7; R4 is hydrogen, C1 to C4 alkyl, C1 to C4 alkoxy, trifluoromethyl or halo; R6 is hydrogen or C1 to C4 alkyl; R7 is an optionally substituted monocyclic or bicyclic ring system; m is 1 or 2; and n is 0, 1 or 2; with the proviso that B is not O when A is C; are MMP inhibitors useful in the treatment of, inter alia, tissue ulceration, wound repair and skin diseases.