128317-57-7

Basic information

• Product Name: 2-[4-(dimethylamino)phenyl]-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-thiazolidin-4-one
• Synonyms: 2-[4-(dimethylamino)phenyl]-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-thiazolidin-4-one
• CAS NO: 128317-57-7
• Molecular Formula: C₂₂H₂₄N₄O₂S
• Molecular Weight: 408.51656
• Mol File: 128317-57-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[4-(dimethylamino)phenyl]-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-thiazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(dimethylamino)phenyl]-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-thiazolidin-4-one(128317-57-7)
• EPA Substance Registry System: 2-[4-(dimethylamino)phenyl]-3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1,3-thiazolidin-4-one(128317-57-7)

Safety Data

• Hazardous Substances Data: 128317-57-7(Hazardous Substances Data)

Upstream product

• 61098-08-6 4-(4-(dimethylamino)benzylideneamino)-1,2-dihydro-2,3-dimethyl-1-phenylpyrazol-5-one 
• 68-11-1 mercaptoacetic acid 
• 83-07-8 4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one 
• 61098-08-6 (E)-4-[4-dimethylaminobenzylideneamino]-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one 

Relevant articles and documents

THIAZOLIDINONE COMPOUNDS AND USE THEREOF

A pharmaceutical composition containing a compound of Formula (I) for treating an opioid receptor-associated condition. Also disclosed is a method for treating an opioid receptor-associated condition using such a compound. Further disclosed are two sets of thiazolidinone compounds of formula (I): (i) compounds each having an enantiomeric excess greater than 90% and (ii) compounds each being substituted with deuterium.

Synthesis and pharmacological screening of a new series of 3-(4-antipyryl)-2-arylthiazolidin-4-ones

A series of 3-(4-antipyryl)-2-arylthiazolidin-4-one derivatives were synthesized and pharmacologically evaluated for antinociceptive, spasmolytic and cardiovascular activities.The presence of a methoxy-naphthyl or a substituted phenyl group in 2-position