1283189-10-5Relevant articles and documents
Access to biomolecular assemblies through one-pot triple orthogonal chemoselective ligations
Galibert, Mathieu,Renaudet, Olivier,Dumy, Pascal,Boturyn, Didier
, p. 1901 - 1904 (2011)
Three into one will go: The consecutive combination of three orthogonal chemoselective reactions (oxime ligation, thioether addition, and copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC)) in a sequential one-pot approach allows the syntheses of highly sophisticated biomolecular compounds without intervening isolations and protection schemes (see picture; ODN=oligodeoxynucleotide).