128321-65-3

Upstream product

• 4341-24-6 5-methylcyclohexan-1,3-dione 
• 35023-83-7 3-ethoxy-5-methyl-cyclohex-2-enone 
• 74-88-4 methyl iodide 

Downstream Products

• 128321-53-9 (5S,6S)-3-Ethoxy-5,6-dimethyl-6-(4-trimethylsilanyl-but-2-ynyl)-cyclohex-2-enone 
• 128321-53-9 5r,6c-Dimethyl-3-ethoxy-6-<4-(trimethylsilyl)-2-butynyl>-2-cyclohexen-1-one 
• 119333-77-6 (Z)-4r,5c-Dimethyl-4-<4-(trimethylsilyl)-2-butenyl>-3-vinyl-2-cyclohexen-1-one 
• 128321-54-0 (Z)-5r,6c-Dimethyl-3-ethoxy-6-<4-(trimethylsilyl)-2-butenyl>-2-cyclohexen-1-one 
• 128321-55-1 (2S^*,4R^*,4aS^*)-2,3,4,4a,5,8,9,10-Octahydro-4,4a-dimethylbenzocyclooctadien-2-ol 
• 128321-55-1 (2R^*,4R^*,4aS^*)-2,3,4,4a,5,8,9,10-Octahydro-4,4a-dimethylbenzocyclooctadien-2-ol 

Relevant academic research and scientific papers

Synthetic studies towards the phomactins. Concise syntheses of the tricyclic furanochroman and the oxygenated bicyclo[9.3.1]pentadecane ring systems in phomactin A.

A concise synthesis of the tricyclic furanochroman unit 3 found in the PAF antagonist phomactin A (1) isolated from the marine fungus Phoma sp., is described. In complementary studies, a variety of synthetic routes towards the bicyclo[9.3.1]pentadecane ring system 4 in phomactin A were explored. These studies culminated in a synthesis of the substituted ring system 79 containing all the carbon atoms and all the necessary oxygen centres for elaboration to phomactin A itself.

Intramolecular Additions of Allylsilanes to Conjugated Dienones. Direct Stereoselective Syntheses of (+/-)-Neolemnanyl Acetate and (+/-)-Neolemnane

The total synthesis of the marine sesquiterpenes neolemnanyl acetate (1) and neolemnane (2) is reported.An intramolecular allylsilane addition to a conjugated dienone is used to assemble the basic 6,8-fused skeleton.Functionalization of the cyclooctane ri