128322-20-3Relevant academic research and scientific papers
Total synthesis of (+)-mayolide A. Absolute structure of mayolide A, a sacocembrane diterpenoid from the soft coral Sinularia mayi
Nagaoka,Iwashima,Abe,Iguchi,Yamada
, p. 1742 - 1749 (2007/10/02)
The stereoselective total synthesis of (+)-mayolide A (1) was achieved starting from D-mannitol via two crucial steps: stereoselective introduction of a two-carbon unit into the β-position of the butenolide 5 and repeated Claisen rearrangement to produce the side chain. The absolute structure of natural mayolide A from the Okinawan soft coral Sinularia mayi was determined as 2 by the present synthesis.
