128332-25-2

Basic information

• Product Name: (-)-(R)-5-(2-((2-(o-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzene sulfonamide monohydrochloride
• Synonyms: (-)-(R)-5-(2-((2-(o-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzene sulfonamide monohydrochloride
• CAS NO: 128332-25-2
• Molecular Weight: 0
• Mol File: 128332-25-2.mol
• Article Data: 24

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (-)-(R)-5-(2-((2-(o-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzene sulfonamide monohydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(R)-5-(2-((2-(o-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzene sulfonamide monohydrochloride(128332-25-2)
• EPA Substance Registry System: (-)-(R)-5-(2-((2-(o-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzene sulfonamide monohydrochloride(128332-25-2)

Safety Data

• Hazardous Substances Data: 128332-25-2(Hazardous Substances Data)

Usage

General Description

The chemical "(-)-(R)-5-(2-((2-(o-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzene sulfonamide monohydrochloride" is a complex compound used as a medication. It contains a sulfonamide group, which is commonly found in antibiotics and diuretics, and a monohydrochloride salt. The presence of a benzene ring and an ethoxyphenoxy group suggest potential pharmacological activity, possibly related to cardiovascular or central nervous system effects. The compound's specific stereochemistry, indicated by the (-)-(R) prefix, may be important for its biological activity and interactions with other molecules in the body. Further research and analysis are needed to fully understand the properties and potential applications of this chemical.

Upstream product

• 6781-17-5 2-(2-ethoxyphenoxy)-ethylamine 
• 116091-63-5 2-methoxy-5-(2-oxopropyl)benzenesulfonamide 
• 169506-15-4 2-(2-ethyloxyphenoxy)ethyl methanesulfonate 
• 112101-81-2 5-((R)-2-amino-1-propyl)-2-methoxybenzenesulphonamide 
• 521300-99-2 (R)-tamsarocin (-)-camphor-10-sulfonate 
• 106463-17-6 (+)-Tamsulosin 
• 133261-17-3 (R)-2-(2-ethoxyphenoxy)-N-[2-(4-methoxy-3-aminosulfonyl-phenyl)-1-methyl-ethyl]-acetamide 
• 86225-65-2 (R)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide hydrochloride 
• 3259-03-8 2-(o-ethoxyphenoxy)-ethyl bromide 
• 106133-20-4 (R)-tamsulosin 

Relevant articles and documents

Preparation method of tamsulosin hydrochloride crystal form

The invention relates to the technical field of preparation of crystal forms of organic compounds, in particular to a preparation method of a tamsulosin hydrochloride crystal form. The method comprises the following steps: completely dissolving tamsulosin in a solvent at 60-70 DEG C, then dropwise adding acid for reaction for a period of time, conducting cooling to 20-30 DEG C, and conducting filtering, washing and drying to obtain tamsulosin, wherein tamsulosin is a refined product. The method is simple in process, high in yield, high in product purity and suitable for large-scale industrialization.

Preparation method of tamsulosin hydrochloride

The invention provides a preparation method of tamsulosin hydrochloride. Specifically, the preparation method comprises a step of reacting 5-acetonyl-2-methoxybenzenesulfonamide with (R)-1-phenylethylamine under the action of a reducing agent to obtain a compound as shown in a formula (IV) or pharmaceutically acceptable salt thereof, and further comprises a step of preparing tamsulosin hydrochloride from the compound as shown in the formula (IV) or pharmaceutically acceptable salt thereof. The preparation method provided by the invention is high in safety and strong in operability, avoids theuse of a heavy metal catalyst, and has an industrial actual use value.

PROCESS FOR PREPARATION OF HIGH PURITY TAMSULOSIN OR SALT THEREOF

The present invention refers to of the existing method contain pharmaceutically available plasticizer manufacturing method compared to a simple, low-environmentally friendly, purity contain pharmaceutically available plasticizer or contain pharmaceutically available plasticizer hydrochloride provides manufacturing method. (by machine translation)