128348-27-6Relevant academic research and scientific papers
Synthesis of diaryl sulfones at room temperature: Cu-catalyzed cross-coupling of arylsulfonyl chlorides with arylboronic acids
Hu, Feng,Lei, Xiangyang
, p. 1539 - 1542 (2015)
An efficient and convenient method for the synthesis of diaryl sulfones was developed through the Cu-catalyzed cross-couplings of arylsulfonyl chlorides and arylboronic acids at room temperature in open air. This method is characterized by the use of inexpensive and readily available catalyst and substrates, mild reaction conditions, wide functionality tolerance, short reaction times for most substrates, and moderate to good yields. Stitch it up with copper: An efficient and convenient method for the synthesis of diaryl sulfones was developed through the Cu-catalyzed cross- couplings of arylsulfonyl chlorides and arylboronic acids at room temperature in open air.
4-Substituted thiophene- and furan-2-sulfonamides as topical carbonic anhydrase inhibitors
Hartman,Halczenko,Smith,Sugrue,Mallorga,Michelson,Randall,Schwam,Sondey
, p. 3822 - 3831 (2007/10/02)
A series of 4-substituted thiophene- and furan-2-sulfonamides was prepared and was found to possess nanomolar-level potency for inhibition of human carbonic anhydrase II in vitro. Selected examples from this group were further evaluated for their potentia
