128348-36-7

Upstream product

• 62141-76-8 3-<(4-methylphenyl)sulfonyl>thiophene 
• 119731-32-7 4-<(4-methylphenyl)sulfonyl>thiophene-2-sulfonyl chloride 
• 42057-02-3 3-<(4-methylphenyl)thio>thiophene 
• 103-19-5 di(p-tolyl) disulfide 

Downstream Products

• 128348-37-8 4-<<4-(bromomethyl)phenyl>sulfonyl>thiophene-2-sulfonamide 
• 143509-53-9 4-<<4-<<(2-pyridylmethyl)amino>methyl>phenyl>sulfonyl>thiophene-2-sulfonamide 
• 143509-52-8 4-<<4-<(N-methylpiperazino)methyl>phenyl>sulfonyl>thiophene-2-sulfonamide 
• 143509-51-7 4-<<4-(morpholinomethyl)phenyl>sulfonyl>thiophene-2-sulfonamide 
• 119731-25-8 4-<<4-<(n-butylamino)methyl>phenyl>sulfonyl>thiophene-2-sulfonamide 
• 143509-61-9 4-<<4-<(tert-butylamino)methyl>phenyl>sulfonyl>thiophene-2-sulfonamide 

Relevant academic research and scientific papers

4-Substituted thiophene- and furan-2-sulfonamides as topical carbonic anhydrase inhibitors

A series of 4-substituted thiophene- and furan-2-sulfonamides was prepared and was found to possess nanomolar-level potency for inhibition of human carbonic anhydrase II in vitro. Selected examples from this group were further evaluated for their potentia

THIOPHENE SULFONAMIDE ANTIGLAUCOMA AGENTS

Aryl (or aralkyl)-sulfonylthiophene-2-sulfonamides containing a basic functional group as a substituent are efficacious in the treatment of elevated intraocular pressure and glaucoma following topical ocular administration.