128349-75-7Relevant academic research and scientific papers
Synthesis and reductions of cis- and trans-1,4,4a,6,7,8,9,11a-octahydropyridoquinazolin-11-one
Fueloep, F.,Huber, I.,Bernath, G.,Toth, G.,Pricken, A.,Pflegel, P.
, p. 109 - 110 (2007/10/02)
Through the condensation of cis- and trans-2-amino-4-cyclohexene-1-carboxylic acid (1 and 5) with O-methyl-δ-valerolactim, octahydropyridoquinazolin-11-one diastereomers 2, 6 were prepared.Their sodium borohydride or polarographic reduction led stereospecifically to decahydro derivatives 3 and 7, while their catalytic reduction resulted in perhydro derivatives 4 and 8.The relative configurations of the compounds prepared were proved by 1H and 13C NMR spectroscopy.
