128350-90-3 Usage
Description
3-HYDROXY-2-OXO-3-TRIFLUOROMETHYL-7-METHYLINDOLINE is a heterocyclic chemical compound with the molecular formula C10H8F3NO2. It features a five-membered ring with a nitrogen atom and is a derivative of indoline. 3-HYDROXY-2-OXO-3-TRIFLUOROMETHYL-7-METHYLINDOLINE is notable for its trifluoromethyl group, which is known to enhance the biological activity and metabolic stability of drug candidates. Additionally, the presence of hydroxy and oxo groups contributes to its chemical reactivity and potential pharmacological properties, making it an important building block in organic synthesis and drug discovery.
Uses
Used in Pharmaceutical Industry:
3-HYDROXY-2-OXO-3-TRIFLUOROMETHYL-7-METHYLINDOLINE is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to improve the biological activity and metabolic stability of drug candidates. The trifluoromethyl group and the heterocyclic structure provide unique properties that can be exploited in the development of new medications.
Used in Agrochemical Industry:
In the agrochemical sector, 3-HYDROXY-2-OXO-3-TRIFLUOROMETHYL-7-METHYLINDOLINE serves as a valuable precursor in the creation of agrochemicals, potentially enhancing the effectiveness and selectivity of pesticides and other agricultural chemicals. Its chemical reactivity allows for the development of compounds with specific target interactions in the field of crop protection.
Used in Organic Synthesis:
3-HYDROXY-2-OXO-3-TRIFLUOROMETHYL-7-METHYLINDOLINE is utilized as a building block in organic synthesis, where its unique structural features and functional groups can be employed to construct a wide range of complex organic molecules for various applications, including the development of new materials and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 128350-90-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,3,5 and 0 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 128350-90:
(8*1)+(7*2)+(6*8)+(5*3)+(4*5)+(3*0)+(2*9)+(1*0)=123
123 % 10 = 3
So 128350-90-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H8F3NO2/c1-5-3-2-4-6-7(5)14-8(15)9(6,16)10(11,12)13/h2-4,16H,1H3,(H,14,15)
128350-90-3Relevant articles and documents
REACTIONS OF HIGHLY ELECTROPHILIC POLYFLUOROCARBONYL COMPOUNDS WITH PRIMARY ARYLAMINES
Chkanikov, N. D.,Sviridov, V. D.,Zelenin, A. E.,Galakhov, M. V.,Kolomiets, A. F.,Fokin, A. V.
, p. 323 - 328 (2007/10/02)
C-Hydroxyalkylation of primary arylamines by highly electrophilic polyfluorocarbonyl compounds results from the direct reaction of the initial reagents and is competitively inhibited by equilibrium N-hydroxyalkylation.The presence of steric hindrances to
