128358-19-0Relevant academic research and scientific papers
On the Scope of Asymmetric Nitrile Oxide Cycloadditions with Oppolzer's Chiral Sultam. Total Syntheses of (+)-Hepialone, (-)-(1R,3R,5S)-1,3-Dimethyl-2,9-dioxabicyclooctane
Curran, Dennis P.,Heffner, Timothy A.
, p. 4585 - 4595 (2007/10/02)
Cycloadditions of nitrile oxides with acryloyl derivatives of Oppolzer's chiral sultam produce stereoisomeric Δ2-isoxazolines in ratios of about 90/10 at 25 deg C.The major diastereomers can be isolated in pure form in 70-88percent yield.Synthe
