128359-83-1

Basic information

• Product Name: 5,6-epoxy-α-tocopherylquinone
• CAS NO: 128359-83-1
• Molecular Weight: 462.714
• Mol File: 128359-83-1.mol

Chemical Properties

• CAS DataBase Reference: 5,6-epoxy-α-tocopherylquinone(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-epoxy-α-tocopherylquinone(128359-83-1)
• EPA Substance Registry System: 5,6-epoxy-α-tocopherylquinone(128359-83-1)

Safety Data

• Hazardous Substances Data: 128359-83-1(Hazardous Substances Data)

Upstream product

• 40811-59-4 1,2-dilinolenoyl-sn-glycero-3-phosphocholine 
• 59-02-9 Tocopherol 

Relevant articles and documents

Oxidation of alpha-tocopherol during the peroxidation of dilinoleoylphosphatidylcholine in liposomes.

Liposomal suspensions of dilinoleoylphosphatidylcholine (DLPC) containing alpha-tocopherol (0.1 mol%, based on DLPC were oxidized at 37 degrees C. The oxidation was initiated by a lipid-soluble or water-soluble free radical initiator, or by the addition of CuSO4 and fructose. In all the oxidation systems, alpha-tocopherol suppressed the formation of DLPC hydroperoxides until all the alpha-tocopherol had been depleted. The oxidation products of alpha-tocopherol were 8a-alkyldioxy-alpha-tocopherones, 5,6-epoxy-alpha-tocopherylquinone, 2,3-epoxy-alpha-tocopherylquinone, and alpha-tocopherylquinone. The 8a-alkyldioxy-alpha-tocopherones were decomposed in the liposomes primarily by being hydrolyzed to produce alpha-tocopherylquinone. The results indicate that alpha-tocopherol can trap peroxyl radical to form 8a-alkyldioxy-alpha-tocopherones which are hydrolyzed to alpha-tocopherylquinone in phospholipid bilayers. In another oxidation pathway, alpha-tocopherol may be oxidized by peroxyl radicals to form isomeric epoxy-alpha-tocopherylquinones.