128360-08-7

Upstream product

• 129886-97-1 2,4,4-Trimethyl-3a,9b-dihydro-4H-chromeno[4,3-d]oxazole-8-carbonitrile 
• 65018-90-8 3,4-epoxy-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-carbonitrile 
• 123595-70-0 (3RS,4SR)-4-amino-3-hydroxy-2,2-dimethylchroman-6-carbonitrile 
• 108-24-7 acetic anhydride 

Downstream Products

• 89316-86-9 N-((3S,4S)-6-Cyano-3-hydroxy-2,2-dimethyl-chroman-4-yl)-acetamide 

Relevant academic research and scientific papers

Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents

A new method for the treatment of ischemic conditions and arrhythmia is disclosed. The method uses compounds of the formula STR1 wherein A can be --CH2 --, --O--, --NR9 --, --S--, --SO--, --SO2 --; X can be oxygen or sulfu

The action of diethylaminosulphur trifluoride (dast) on trans-4-amido- 3-Chromanols: Preparation of cis-amidoalcohols via oxazolines

Treatment of a variety of trans -4-amido-3-chromanols (3) with DAST gives oxazolines (4) which can be hydrolysed to give the corresponding cis-amido-alcohols (5). Similar treatment of the trans-4-ureido-3-chromanol (8) gave the unexpected 4-fluoro-3-ureid

Synthesis and antihypertensive activity of 4-(substituted-carbonylamino)-2H-1-benzopyrans

The synthesis and antihypertensive activity of a series of novel 4-(substituted-carbonylamino)-2H-1-benzopyran-3-ols, administered orally to conscious spontaneously hypertensive rats, are described. Optimum activity was observed for compounds with alkyl,