128360-08-7

Basic information

• Product Name: N-(6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-4-yl)acetamide
• CAS NO: 128360-08-7
• Molecular Formula: C₁₄H₁₆N₂O₃
• Molecular Weight: 260.2884
• Mol File: 128360-08-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 482.1°C at 760 mmHg
• Flash Point: 245.3°C
• Density: 1.26g/cm³
• Vapor Pressure: 4.19E-10mmHg at 25°C
• Refractive Index: 1.582
• CAS DataBase Reference: N-(6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-4-yl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-4-yl)acetamide(128360-08-7)
• EPA Substance Registry System: N-(6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-4-yl)acetamide(128360-08-7)

Safety Data

• Hazardous Substances Data: 128360-08-7(Hazardous Substances Data)

Upstream product

• 65018-90-8 3,4-epoxy-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-carbonitrile 
• 123595-70-0 (3RS,4SR)-4-amino-3-hydroxy-2,2-dimethylchroman-6-carbonitrile 
• 108-24-7 acetic anhydride 
• 129886-97-1 2,4,4-Trimethyl-3a,9b-dihydro-4H-chromeno[4,3-d]oxazole-8-carbonitrile 

Downstream Products

• 89316-86-9 N-((3S,4S)-6-Cyano-3-hydroxy-2,2-dimethyl-chroman-4-yl)-acetamide 

Relevant articles and documents

Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents

A new method for the treatment of ischemic conditions and arrhythmia is disclosed. The method uses compounds of the formula STR1 wherein A can be --CH2 --, --O--, --NR9 --, --S--, --SO--, --SO2 --; X can be oxygen or sulfu

The action of diethylaminosulphur trifluoride (dast) on trans-4-amido- 3-Chromanols: Preparation of cis-amidoalcohols via oxazolines

Treatment of a variety of trans -4-amido-3-chromanols (3) with DAST gives oxazolines (4) which can be hydrolysed to give the corresponding cis-amido-alcohols (5). Similar treatment of the trans-4-ureido-3-chromanol (8) gave the unexpected 4-fluoro-3-ureid