128360-37-2Relevant academic research and scientific papers
Synthesis and antihypertensive activity of 4-(substituted-carbonylamino)-2H-1-benzopyrans
Ashwood,Cassidy,Coldwell,Evans,Hamilton,Howlett,Smith,Stemp
, p. 2667 - 2672 (1990)
The synthesis and antihypertensive activity of a series of novel 4-(substituted-carbonylamino)-2H-1-benzopyran-3-ols, administered orally to conscious spontaneously hypertensive rats, are described. Optimum activity was observed for compounds with alkyl,
Cardioselective Antiischemic ATP-Sensitive Potassium Channel Openers. 2. Structure-Activity Studies on Benzopyranylcyanoguanidines: Modification of the Benzopyran Ring
Atwal, Karnail S.,Grover, Gary J.,Ferrara, Francis N.,Ahmed, Syed Z.,Sleph, Paul G.,et al.
, p. 1966 - 1973 (2007/10/02)
The ATP-sensitive potassium channel (KATP) openers are of considerable interest as myocardial protecting agents.However, there exists a narrow window of safety for the use of first-generation compounds as antiischemic agents due to their powerf
