1283651-60-4Relevant academic research and scientific papers
Separation of betti reaction product enantiomers: Absolute configuration and inhibition of botulinum neurotoxin A
Cardellina, John H.,Vieira, Rebecca C.,Eccard, Vanessa,Skerry, Janet,Montgomery, Vicki,Campbell, Yvette,Roxas-Duncan, Virginia,Leister, William,Leclair, Christopher A.,Maloney, David J.,Padula, Daniele,Pescitelli, Gennaro,Khavrutskii, Ilja,Hu, Xin,Wallqvist, Anders,Smith, Leonard A.
body text, p. 396 - 401 (2011/07/09)
The racemic product of the Betti reaction of 5-chloro-8-hydroxyquinoline, benzaldehyde, and 2-aminopyridine was separated by chiral HPLC to determine which enantiomer inhibited botulinum neurotoxin serotype A. When the enantiomers unexpectedly proved to h
