1283728-64-2

Upstream product

• 937021-07-3 2-(4-azidobutoxy)benzoic acid 2-methoxyethyl ester 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 6289-19-6 O-α,α-dimethylpropargyl N-phenylcarbamate 
• 937021-10-8 2-{4-[4-(1-hydroxy-1-methyl-ethyl)-[1,2,3]triazol-1-yl]-butoxy}-benzoic acid 2-methoxyethyl ester 
• 103-71-9 phenyl isocyanate 

Relevant academic research and scientific papers

Extending triazolyl-based release under mildly acidic conditions to give aniline derivatives

Triazolyl derivatives of anilines were prepared and evaluated as releasing systems at mildly acidic pH values. Two triazolyl derivatives showed convenient pH sensitivity, being stable at pH 7.3 and rapidly hydrolyzed at pH values below 5. A generalized me

Investigations into competitive cycloaddition/cyclization or elimination from 1,1-dimethyl-propargylcarbamates of anilines

The copper-catalyzed reaction of 1,1-dimethyl-O-propargyl aniline carbamates was studied and revealed the unexpected formation of oxazolidin-2-ones and alkylamines. An in-depth study of the reaction conditions showed that the formation of these products was highly dependent on the solvent, copper catalyst and aniline substituents. The reaction can be oriented towards oxazolidinones in pyridine and alkylamines in ethanol, whereas cycloaddition can be achieved in dry tetrahydrofuran.