128376-16-9

Upstream product

• 882-33-7 diphenyldisulfane 
• 32249-55-1 (20S)-3α,5-cyclo-20-formyl-6β-methoxy-5α-pregnane 
• 128376-14-7 (2R,3R,5S)-6-[1,3]Dithian-2-ylidene-2-((1aR,3aR,3bS,5aS,6S,8aS,8bS,10R,10aR)-10-methoxy-3a,5a-dimethyl-hexadecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)-5-methyl-hexane-2,3-diol 
• 128387-95-1 (4S,6R)-6-[(R)-1-Hydroxy-1-((1aR,3aR,3bS,5aS,6S,8aS,8bS,10R,10aR)-10-methoxy-3a,5a-dimethyl-hexadecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)-ethyl]-4-methyl-tetrahydro-pyran-2-one 
• 128376-15-8 (R)-1-((1aR,3aR,3bS,5aS,6S,8aS,8bS,10R,10aR)-10-Methoxy-3a,5a-dimethyl-hexadecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)-1-((8R,10S)-10-methyl-7-oxa-1,5-dithia-spiro[5.5]undec-8-yl)-ethanol 
• 128376-13-6 (3S,5R)-5-[(R)-1-Hydroxy-1-((1aR,3aR,3bS,5aS,6S,8aS,8bS,10R,10aR)-10-methoxy-3a,5a-dimethyl-hexadecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)-ethyl]-3-methyl-dihydro-furan-2-one 
• 128376-12-5 (R)-6-((1aR,3aR,3bS,5aS,6S,8aS,8bS,10R,10aR)-10-Methoxy-3a,5a-dimethyl-hexadecahydro-cyclopenta[a]cyclopropa[2,3]cyclopenta[1,2-f]naphthalen-6-yl)-3,6-dimethyl-pyran-2,5-dione 
• 63762-41-4 2-lithio-4-methylfuran 

Relevant academic research and scientific papers

STEREOCONTROLLED SYNTHESIS OF THE WITHANOLIDE D SIDE CHAIN FROM 20-OXOSTEROID

A new procedure for the construction of the withanolide D side chain starting from 20-oxopregnane is described.The key reactions are stereochemical control of C-20 and C-22 positions involving stereoselective hydrogenation of the enone 4, and an efficient