128385-82-0

Basic information

• Product Name: (1R,2S,3R,5R)-2,3-epoxy-5-isopropenyl-2-methylcyclohex-2-enol
• Synonyms: (1R,2S,3R,5R)-2,3-epoxy-5-isopropenyl-2-methylcyclohex-2-enol
• CAS NO: 128385-82-0
• Molecular Weight: 168.236
• Mol File: 128385-82-0.mol

Chemical Properties

• CAS DataBase Reference: (1R,2S,3R,5R)-2,3-epoxy-5-isopropenyl-2-methylcyclohex-2-enol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,3R,5R)-2,3-epoxy-5-isopropenyl-2-methylcyclohex-2-enol(128385-82-0)
• EPA Substance Registry System: (1R,2S,3R,5R)-2,3-epoxy-5-isopropenyl-2-methylcyclohex-2-enol(128385-82-0)

Safety Data

• Hazardous Substances Data: 128385-82-0(Hazardous Substances Data)

Upstream product

• 36616-60-1 (1R,4R,6R)-4-isopropenyl-1-methyl-7-oxabicyclo[4.1.0]heptan-2-one 
• 6485-40-1 (R)-Carvone 

Downstream Products

• 191410-13-6 1-((1R,3S,5R,6S)-5-Hydroxy-6-methyl-7-oxa-bicyclo[4.1.0]hept-3-yl)-ethanone 
• 214212-06-3 (1S,2R,4R,6S)-6-fluoro-4-isopropenyl-1-methylcyclohexane-1,2-diol 
• 214212-08-5 methanesulfonic acid (1R,2S,3S,5R)-3-fluoro-2-hydroxy-5-isopropenyl-2-methylcyclohexyl ester 
• 123836-61-3 <3S-(1Z,3β,5α)>-<3-Fluoro-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylenecyclohexylidene>ethanol 
• 123836-62-4 <1R-(1β,3Z,5α)>-<<3-(2-Chloroethylidene)-5-fluoro-4-methylenecyclohexyl>oxy>(1,1-dimethylethyl)dimethylsilane 
• 123836-63-5 <3S-(1Z,3α,5β)>-<2-<3-Fluoro-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylenecyclohexylidene>ethyl>diphenylphosphine Oxide 
• 214212-12-1 (1S,3R,5S,6S)-5-fluoro-6-methyl-7-oxabicyclo[4.1.0]heptan-3-ol 
• 214212-15-4 (1S,3S,5R)-5-((tert-butyldimethylsilanyl)oxy)-3-fluoro-2-methylenecyclohexanol 
• 214212-21-2 (Z,3S,5R)-[5-((tert-butyldimethylsilanyl)oxy)-3-fluoro-2-methylenecyclohexylidene]acetic acid methyl ester 
• 214212-17-6 Methanesulfonic acid (1S,3S,5R)-5-(tert-butyl-dimethyl-silanyloxy)-3-fluoro-2-methylene-cyclohexyl ester 
• 214212-19-8 [(4R,6S)-phenylselanyl]acetic acid [4-((tert-butyldimethylsilanyl)oxy)-6-fluorocyclohex-1-enyl]methyl ester 
• 214212-20-1 (3'S,5'R)-[5'-((tert-butyldimethylsilanyl)oxy)-3'-fluoro-2'-methylenecyclohexyl](phenylselanyl)acetic acid methyl ester 
• 57429-67-1 3,5-dinitrobenzoate ester of (+)-trans-carveol 
• 1154606-95-7 tert-butyl{[(1R,2R,4R,6R)-4-isopropenyl-1-methyl-7-oxabicyclo[4.1.0]hept-2-yl]oxy}diphenylsilane 

Relevant articles and documents

Synthesis of the four epimeric tosylates of (5R)-2,3-epoxy-5-isopropenyl-cyclohexanol

Described is the synthesis of the four optically pure epoxytosylates 5, 6, 9 and 12, each with four chiral centers determined, from a single starting material, (R)(-) carvone.

VITAMIN D RECEPTOR ACTIVATORS AND METHODS OF MAKING

The invention relates to compounds that are vitamin D receptor activators, compositions comprising such compounds, methods of using such compounds and compositions, processes for preparing such compounds, and intermediates obtained during such processes.

(R)-Carvone as chiral template for the synthesis of some polyols

Some (4S,6R,7R) 4,6,7-trihydroxyheptyl derived building blocks have been obtained from (R)-carvone as the chiral template.A key-step is the Baeyer-Villiger oxidation of a suitable intermediate.

Efficient Enantiospecific Synthesis of Key A-Ring Synthons for the Preparation of 1α,25-Dihydroxyvitamin D3 Using a Chromium((II)-Mediated Reaction

Key A-ring synthons for the synthesis of 1α,25-dihydroxyvitamin D3 have been prepared efficiently from (R)-(-)-carvone by use of diastereoselective chromium(II)-mediated addition of an allylic halide to an aldehyde as a key step.