128404-88-6

Upstream product

• 61636-28-0 3-(2-amino-1,3-thiazol-4-yl)coumarin 
• 90-02-8 salicylaldehyde 
• 29310-88-1 3-bromoacetylcoumarin 

Downstream Products

• 87503-74-0 2-chloro-N-[4-(2-oxo-2H-chromen-3-yl)thiazol-2-yl]acetamide 
• 90-02-8 salicylaldehyde 
• 848903-49-1 3-[2-(2-hydroxy-benzylamino)-thiazol-4-yl]-chromen-2-one 
• 128404-95-5 2-(2-hydroxyphenyl)-3-(4-(2-oxo-2H-1-benzopyran-3-yl)-2-thiazolyl)-4-thiazolidinone 

Relevant academic research and scientific papers

Novel approach for the rapid and efficient synthesis of heterocyclic Schiff bases and azetidinones under microwave irradiation

A series of compounds, viz. 3″-chloro-4″-(substituted phenyl)-1″-[4-(coumarin-3-yl)thiazol-2-yl]-2″-azetidinones 4a-j have been prepared by the reaction of 2-N-(substituted benzylidene)imino-4- (coumarin-3-yl)lhiazoles 3a-j with chloroacetyl chloride in m

REACTION OF MERCAPTOACETIC ACID AND CHLOROACETYL CHLORIDE WITH BENZALAMINO THIAZOLYL COUMARINS

2-Aryl-3--4-thiazolidinones (III), have been synthesized by the reaction of Schiff's bases (II) derived from 3-(2-amino-4-thiazolyl)-2H-1-benzopyran-2-ones (I) with mercaptoacetic acid.The Schiff's bases on reaction with chloroacetyl chloride in the presence of triethylamine in dioxane gave chloroacetamido derivative (IV) instead of expected compound V.