128405-19-6Relevant academic research and scientific papers
DABCO- and DBU-promoted one-pot reaction of N-sulfonyl ketimines with Morita-Baylis-Hillman carbonates: A sequential approach to (2-hydroxyaryl)nicotinate derivatives
Guin, Soumitra,Gupta, Raman,Majee, Debashis,Samanta, Sampak
, p. 2771 - 2778 (2018)
An intriguing DABCO-catalyzed and DBU-promoted one-pot synthesis of an important class of (2-hydroxyaryl)pyridine derivatives bearing a carboxylate or a nitrile group suitably placed at C3 position of the aza-ring has been achieved in acceptable chemical yields with a broad functional group tolerance. This sequential C-C/C-N bond making process proceeds through a regioselective allylic alkylation/aza-Michael reaction between MBH carbonates derived from an acrylate/acrylonitrile and N-sulfonyl ketimines as C,N-binucleophiles catalyzed by DABCO, followed by elimination of SO2 under the influence of base and subsequent aromatization in an open atmosphere.
NITRILES IN HETEROCYCLIC SYNTHESIS: A NOVEL ROUTE FOR THE SYNTHESIS OF NAPHTHODIPYRANS, PYRIDINES. 2H- AND 4H-PYRANS
Elagamey, Abdel Ghani A.,El-Taweel, Fathy M. A.,Sowellim, Salah Z. A.,Sofan, Mamdouh A.,Elnagdi, Mohamed H.
, p. 524 - 534 (2007/10/02)
Naphthodipyrans, naphthodipyrans and naphthodipyrans were synthesized by the reaction of cinnamonitriles with 2,3-, 1,5-, 1,6-naphthalenediols, respectively.Polysubstituted pyridines, 2H-pyrans and 4H-pyrans were
