128408-09-3Relevant academic research and scientific papers
Facile one-pot syntheses of amidines and enamines from oximes via Beckmann rearrangement using trifluoromethanesulfonic anhydride
Takuwa, Tomofumi,Minowa, Tomofumi,Onishi, Jim Yoshitaka,Mukaiyama, Teruaki
, p. 1717 - 1725 (2004)
Iminocarbocation intermediates were in situ-generated by treating various oximes with trifluoromethanesulfonic anhydride (Tf2O) in the presence of triethylamine in toluene and nucleophilic trapping with amines or sodium enolates under mild conditions afforded the corresponding amidines and enamines. Some of the thus-obtained enamines were converted to 2-substituted 4-oxo-3-quinolinecarboxylic acid derivatives by subsequent intramolecular Friedel-Crafts acylation.
Facile one-pot syntheses of amidines and enamines from oximes via Beckmann rearrangement using trifluoromethansulfonic anhydride
Takuwa, Tomofumi,Minowa, Tomofumi,Onishi, Jim Yoshitaka,Mukaiyama, Teruaki
, p. 322 - 323 (2007/10/03)
Facile one-pot syntheses of amidines and enamines were achieved by trapping carbocation intermediates that were formed by Beckmann rearrangement of oximes with amines and carbon nucleophiles, respectively, under mild conditions.
