1284211-15-9Relevant academic research and scientific papers
Direct conversion of benzylic and allylic alcohols to phosphonates
Barney, Rocky J.,Richardson, Rebekah M.,Wiemer, David F.
supporting information; experimental part, p. 2875 - 2879 (2011/05/19)
Benzyl phosphonate esters often serve as reagents in Horner-Wadsworth- Emmons reactions. In most cases, they can be prepared from benzylic alcohols via formation of the corresponding halide followed by an Arbuzov reaction. To identify a more direct synthesis of phosphonate esters, we have developed a one-flask procedure for conversion of benzylic and allylic alcohols to the corresponding phosphonates through treatment with triethyl phosphite and ZnI2.
