1284216-75-6Relevant academic research and scientific papers
Preparation and application of air-stable P,N-bidentate ligands for the selective synthesis of δ-lactone via the palladium-catalyzed telomerization of 1,3-butadiene with carbon dioxide
Dai, Yao,Feng, Xiujuan,Wang, Bin,He, Ren,Bao, Ming
experimental part, p. 4309 - 4314 (2012/01/13)
Air-stable P,N-bidentate ligands L1-L7 with cyclic secondary amine moieties linked to the benzene rings of triphenylphosphine were designed and prepared. The chelating coordination mode of the P,N-bidentate ligands to the Pd(II) center was confirmed by determining the X-ray structures of the Pd(II) complexes C1 and C2 derived from ligands L1 and L2, respectively. The ligands were used for the selective synthesis of δ-lactone through the palladium (Pd)-catalyzed telomerization of 1,3-butadiene with carbon dioxide. The highest yield (60% with 79% selectivity) was observed using the Pd2(dba) 3/4-(2-(diphenylphosphino)phenyl)morpholine (L2) catalyst system.
Palladium-catalyzed mono-α-arylation of acetone with aryl halides and tosylates
Hesp, Kevin D.,Lundgren, Rylan J.,Stradiotto, Mark
supporting information; experimental part, p. 5194 - 5197 (2011/06/10)
We report the first example of selective Pd-catalyzed mono-α- arylation of acetone employing aryl chlorides, bromides, iodides, and tosylates. The use of appropriately designed P,N-ligands proved to be the key to controlling the reactivity and selectivity. The reaction affords good yields with substrates containing a range of functional groups at modest Pd loadings using Cs2CO3 as the base and employing acetone as both a reagent and the solvent.(Figure Presented)
