1284220-85-4Relevant academic research and scientific papers
Driving catalyst reoxidation in wacker cyclizations with acetal-based metal-hydride abstractors
Cochrane, Nikki A.,Brookhart, Maurice S.,Gagne, Michel R.
, p. 2457 - 2460 (2011)
In traditional Wacker processes, Pd(II) becomes reduced to Pd(0) after C-O bond formation and β-H elimination and must be reoxidized to the electrophilic Pd(II) state via a stoichiometric oxidant such as benzoquinone, CuCl2, or O2. We report herein a Pt-catalyzed Wacker-type process that regenerates the electrophilic Pt2+ state by H - abstraction from a [Pt]-H using an oxocarbenium ion generated from an acetal or ketal under acidic conditions.
