1284224-16-3

Basic information

• Product Name: N-cyclohexyl-6-methyl-1-phenyl-1H-2-aminobenzimidazole
• Synonyms: N-cyclohexyl-6-methyl-1-phenyl-1H-2-aminobenzimidazole
• CAS NO: 1284224-16-3
• Molecular Weight: 305.423
• Mol File: 1284224-16-3.mol

Chemical Properties

• CAS DataBase Reference: N-cyclohexyl-6-methyl-1-phenyl-1H-2-aminobenzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: N-cyclohexyl-6-methyl-1-phenyl-1H-2-aminobenzimidazole(1284224-16-3)
• EPA Substance Registry System: N-cyclohexyl-6-methyl-1-phenyl-1H-2-aminobenzimidazole(1284224-16-3)

Safety Data

• Hazardous Substances Data: 1284224-16-3(Hazardous Substances Data)

Upstream product

• 3878-67-9 N-phenyl-N'-cyclohexyl carbodiimide 
• 583-68-6 2-bromo-p-toluidine 

Relevant articles and documents

A protocol to 2-aminobenzimidazoles via copper-catalyzed cascade addition and cyclization of o-haloanilines and carbodiimides

An efficient strategy for the synthesis of a variety of 2-animobenzimidazole derivatives has been developed. The reaction proceeded from o-haloanilines and carbodiimides via copper(I)-catalyzed domino reaction in the presence of tert-butoxide to afford the corresponding 2-animobenzimidazole derivatives in good to excellent yields. o-Haloanilines could be o-iodoaniline, o-bromoaniline, and o-chloroaniline derivatives. Carbodiimides could be symmetrical and unsymmetrical substrates with aryl or alkyl substituents. The reaction exhibited a good regioselectivity when unsymmetrical carbodiimides were employed.