1284293-40-8Relevant articles and documents
Transition metal-mediated C=O and C=C bond-forming reactions: A regioselective strategy for the synthesis of imidazo[1,2- A ]pyridines and imidazo[1,2- A ]pyrazines
Cao, Hua,Liu, Xiaohang,Liao, Jinqiang,Huang, Jianping,Qiu, Huifang,Chen, Qinlin,Chen, Yaoyi
, p. 11209 - 11214 (2014)
A novel and convenient transformation for the regiospecific synthesis of functionalized imidazo[1,2-a]pyridine aldehydes/ketones and 3-vinyl imidazo[1,2-a]pyridines has been developed via copper(I)- and palladium(II)-catalyzed cyclization. The one-pot reaction proceeds smoothly with commercially available catalysts and affords the products in moderate to good yields. It represents an efficient approach for the formation of C-N, C=O, and C=C bonds under mild conditions.
I2-catalyzed intramolecular oxidative amination of C(sp3)-H bond: Efficient access to 3-acylimidazo[1,2-: A] pyridines under neat condition
Huang, Lilan,Yin, Wenqing,Wang, Jian,Gan, Chunfang,Huang, Yanmin,Huang, Chusheng,He, Yimiao
, p. 2381 - 2385 (2019/02/01)
An efficient and "green" protocol for the synthesis of 3-acylimidazo[1,2-a]pyridines through intramolecular oxidative α-amination of carbonyl compounds has been developed. The reaction proceeds smoothly utilizing I2 as a catalyst and H2O2 as an oxidant under neat condition with broad substrate scope. Several complex nitrogen-containing fused rings are conveniently constructed, which are not easy to access by traditional methods.
Convenient two-step one-pot synthesis of 3-substituted imidazo[1,2-a]pyridines and imidazo[1,2-b]pyridazines
Fan, Hongli,Li, Fenghai
, (2018/05/23)
Abstract: A convenient and novel two-step one-pot method for the synthesis of 3-substituted imidazo[1,2-a]pyridines and 3-substituted imidazo[1,2-b]pyridazines was developed through the reaction of heterocyclic amines and N,?N-dimethylformamide dimethyl a