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Usage

Uses

Used in Pharmaceutical Synthesis:
(6-Bromoimidazo[1,2-a]pyridin-3-yl)phenylmethanone is used as a key intermediate in the pharmaceutical industry for the development of new drugs. Its unique chemical structure allows it to modulate various biological targets, making it a promising candidate for the treatment of different diseases.
Used in Agrochemical Synthesis:
In the agrochemical industry, (6-Bromoimidazo[1,2-a]pyridin-3-yl)phenylmethanone is utilized as a vital component in the creation of novel pesticides and other agrochemical products. Its ability to interact with specific biological targets can lead to the development of more effective and targeted pest control solutions.
Used in Organic Synthesis as a Reagent:
(6-Bromoimidazo[1,2-a]pyridin-3-yl)phenylmethanone serves as a valuable reagent in organic synthesis, enabling the production of a wide range of chemical compounds with diverse applications.
Used in Medicinal Chemistry Research:
(6-Bromoimidazo[1,2-a]pyridin-3-yl)phenylmethanone is used as a research tool in medicinal chemistry to study its potential to modulate biological targets, which could lead to the discovery of new therapeutic agents.
Used in Material Science:
(6-Bromoimidazo[1,2-a]pyridin-3-yl)phenylmethanone is also of interest in the field of material science, where it may contribute to the development of innovative organic materials with unique properties and potential applications in various industries.

Upstream product

• 70-11-1 α-bromoacetophenone 
• 1072-97-5 5-bromo-2-pyridylamine 
• 2579-22-8 Phenylpropargyl aldehyde 
• 138240-34-3 (E)-N’-(5-bromopyridin-2-yl)-N,N-dimethylformamidine 
• 22259-90-1 3-((5-bromopyridin-2-yl)amino)-1-phenylpropan-1-one 

Downstream Products

• 328062-45-9 6-phenylimidazo[1,2-a]pyridine 

Relevant academic research and scientific papers

Transition metal-mediated C=O and C=C bond-forming reactions: A regioselective strategy for the synthesis of imidazo[1,2- A ]pyridines and imidazo[1,2- A ]pyrazines

A novel and convenient transformation for the regiospecific synthesis of functionalized imidazo[1,2-a]pyridine aldehydes/ketones and 3-vinyl imidazo[1,2-a]pyridines has been developed via copper(I)- and palladium(II)-catalyzed cyclization. The one-pot reaction proceeds smoothly with commercially available catalysts and affords the products in moderate to good yields. It represents an efficient approach for the formation of C-N, C=O, and C=C bonds under mild conditions.

Gold-catalyzed synthesis of 3-acylimidazo[1,2-a]pyridines via carbene oxidation

A convenient gold-catalyzed strategy for the synthesis of imidazo[1,2-a]pyridine derivatives has been developed via gold carbene complexes. This transformation opens a new synthetic route to a variety of 3-carbonyl-substituted imidazo[1,2-a]pyridines using air as oxidant affording the products in good yields.

I2-catalyzed intramolecular oxidative amination of C(sp3)-H bond: Efficient access to 3-acylimidazo[1,2-: A] pyridines under neat condition

An efficient and "green" protocol for the synthesis of 3-acylimidazo[1,2-a]pyridines through intramolecular oxidative α-amination of carbonyl compounds has been developed. The reaction proceeds smoothly utilizing I2 as a catalyst and H2O2 as an oxidant under neat condition with broad substrate scope. Several complex nitrogen-containing fused rings are conveniently constructed, which are not easy to access by traditional methods.

Metal-Free Aerobic Oxidative Selective C-C Bond Cleavage in Heteroaryl-Containing Primary and Secondary Alcohols

A transition-metal-free aerobic oxidative selective C-C bond-cleavage reaction in primary and secondary heteroaryl alcohols is reported. This reaction was highly efficient and tolerated various heteroaryl alcohols, generating a carboxylic acid derivative and a neutral heteroaromatic compound. Experimental studies combined with density functional theory calculations revealed the mechanism underlying the selective C-C bond cleavage. This strategy also provides an alternative simple approach to carboxylation reaction.

Convenient two-step one-pot synthesis of 3-substituted imidazo[1,2-a]pyridines and imidazo[1,2-b]pyridazines

Abstract: A convenient and novel two-step one-pot method for the synthesis of 3-substituted imidazo[1,2-a]pyridines and 3-substituted imidazo[1,2-b]pyridazines was developed through the reaction of heterocyclic amines and N,?N-dimethylformamide dimethyl a

A revised approach to the synthesis of 3-acyl imidazo[l,2-a] pyridines

3-Acyl imidazo[l,2-a]pyridines with no substituent at position 2 were obtained in moderate to good yields in an improved version of the Tisler protocol for the synthesis of imidazo[l,2-x]azines. It was found that yields are significantly improved if the r