128457-29-4Relevant academic research and scientific papers
Reactions of 5,5-dimethyl-4-methylene-1,3-dioxolan-2-one with amines in the presence of palladium catalyst
Shi, Min,Shen, Yu-Mei,Chen, Ya-Jun
, p. 245 - 257 (2007/10/03)
In the reaction of 5,5-dimethyl-4-methylene-1,3-dioxolan-2-one with primary amines in the presence of Pd(0) catalyst, the 3-alkyl-4-hydroxy-4,5,5-trimethyloxazolidin-2-ones (1) are obtained as the major products, along with the formation of ring opened products at room temperature. On the other hand, 3-alkyl-5,5-dimethyl-4-methyloxazolidin-2-ones (2) are obtained as reaction products in high yields at high temperature. But in the absence of Pd(0) catalyst, the ring opened compounds alkylcarbamic acid 1,1-dimethyl-2-oxopropyl esters (3) are formed exclusively. In addition, in the reaction of 5,5-dimethyl-4-methylene-1,3-dioxolan-2-one with secondary amines, the ring opened compounds were obtained as the sole products. A plausible mechanism for the formation of 1 and 2 is proposed.
Reactions of 5-methylene-1,3-dioxolan-2-ones with amines. Synthesis of 2-oxazolidinones
Chernysheva,Bogolyubov,Semenov
, p. 216 - 224 (2007/10/03)
The reaction of 5-methylene-1,3-dioxolan-2-ones with aromatic or aliphatic amines as well as with the sodium salts of amino acids leads to 4-hydroxy-2-oxazolidinones. The reaction conditions depend on the basicity of the amines. The use of o-phenylenediamine in this reaction leads to the formation of a new heterocyclic system. 1999 KluwerAcademic/Plenum.
A simple synthesis of oxazolidinones in one step from carbon dioxide
Fournier,Bruneau,Dixneuf
, p. 1721 - 1722 (2007/10/02)
The reaction of carbon dioxide, propargyl alcohol derivatives and primary amines, catalysed by phosphine, gives N-substituted 4-methylene-oxazolidin-2-ones.
