128459-09-6

Basic information

• Product Name: N-METHOXYDIACETAMIDE
• Synonyms: N-METHOXYDIACETAMIDE;N,N-DIACETYL-O-METHYLHYDROXYLAMINE;N,N,N-DIACETYLMETHOXYAMINE;N-ACETYL-N-METHOXYACETAMIDE;Methoxydiacetamide;selectiveacetylatingreagent]95+%;N-Methoxydiacetamide [Selective Acetylating Reagent];[Selective Acetylating Reagent]
• CAS NO: 128459-09-6
• Molecular Formula: C₅H₉NO₃
• Molecular Weight: 131.13
• Product Categories: Hydroxylamines;Hydroxylamines (N-Substituted);Hydroxylamines (O-Substituted)
• Mol File: 128459-09-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 22 °C
• Boiling Point: 74 °C / 12mmHg
• Flash Point: 86 °C
• Appearance: /
• Density: 1.12 g/mL at 20 °C(lit.)
• Vapor Pressure: 3.25mmHg at 25°C
• Refractive Index: n20/D 1.447
• BRN: 3537117
• CAS DataBase Reference: N-METHOXYDIACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHOXYDIACETAMIDE(128459-09-6)
• EPA Substance Registry System: N-METHOXYDIACETAMIDE(128459-09-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: NA 1993 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 128459-09-6(Hazardous Substances Data)

Usage

General Description

N-Methoxydiacetamide, also known as N-Methoxymethylacetamide, is a chemical compound with the molecular formula C5H11NO3. It is a colorless liquid that is commonly used as a solvent in the pharmaceutical and chemical industries. N-Methoxydiacetamide is known for its high solubility in polar and nonpolar solvents, making it a versatile and widely used ingredient in various industrial processes. It is considered to be relatively stable and non-reactive under normal conditions, and it has low acute toxicity. Additionally, N-Methoxydiacetamide is used as an intermediate in the production of pharmaceuticals, dyes, and other organic compounds.

InChI:InChI=1/C5H9NO3/c1-4(7)6(9-3)5(2)8/h1-3H3

Upstream product

• 593-56-6 N-methoxylamine hydrochloride 
• 108-24-7 acetic anhydride 

Downstream Products

• 2901-75-9 (R,S)-N-acetyl phenylalanine 
• 692-04-6 N^ε-Ac-L-Lys 
• 2440-79-1 L-Tyr-OCH₃ 
• 7512-17-6 N-Acetyl-D-glucosamine 
• 29823-47-0 N-benzyl-N-methylacetamide 
• 3306-05-6 N-(2-hydroxy-2-phenylethyl)acetamide 
• 2494-12-4 N-acetyldopamine 
• 1242661-34-2 C₂₄H₂₉F₂IN₂O₂ 
• 676136-59-7 benzyl 4-{[(2R,3S)-3-(acetylamino)-4-(3,5-difluorophenyl)-2-hydroxybutyl]amino}-6-neopentyl-3,4-dihydroquinoline-1(2H)-carboxylate 
• 676136-43-9 benzyl 4-{[(2R,3S)-3-(acetylamino)-4-(3,5-difluorophenyl)-2-hydroxybutyl]amino}-6-ethyl-3,4-dihydroquinoline-1(2H)-carboxylate 
• 866474-13-7 C₂₈H₃₈F₂N₂OS 

Relevant articles and documents

N-METHOXYDIACETAMIDE: A NEW SELECTIVE ACETYLATING AGENT

A simple and efficient method for the direct chemoselective acetylation of primary amines in the presence of alcohols or secondary amines using a new reagent N-methoxydiacetamide is described.