128478-15-9Relevant academic research and scientific papers
Lewis Acid Catalyzed Tandem 1,4-Conjugate Addition/Cyclization of in Situ Generated Alkynyl o-Quinone Methides and Electron-Rich Phenols: Synthesis of Dioxabicyclo[3.3.1]nonane Skeletons
Du, Ji-Yuan,Ma, Yan-Hua,Meng, Fan-Xiao,Chen, Bao-Li,Zhang, Shao-Liang,Li, Qian-Li,Gong, Shu-Wen,Wang, Da-Qi,Ma, Chun-Lin
, p. 4371 - 4374 (2018)
A versatile Lewis acid catalyzed tandem cyclization of in situ generated alkynyl o-quinone methides (o-AQMs) with electron-rich phenols has been developed on the basis of the mode involving an intermolecular 1,4-conjugate addition/6-endo cyclization/1,3-a
Copper-Catalyzed Dehydrative Cyclization of 1-(2-Hydroxyphenyl)propargyl Alcohols with P(O)H Compounds for the Synthesis of 2-Phosphorylmethylbenzofurans
Zhang, Ming,Yang, Jianlin,Xu, Qing,Dong, Chao,Han, Li-Biao,Shen, Ruwei
supporting information, p. 334 - 345 (2018/01/15)
A tetrakis(acetonitrile)copper(I) hexafluorophosphate [Cu(MeCN)PF6]-catalyzed dehydrative reaction of 1-(2-hydroxyphenyl)propargyl alcohols with diarylphosphine oxides has been developed to provide an efficient synthesis of phosphorylated benzo
Aldehyde-Assisted Ruthenium(II)-Catalyzed C-H Oxygenations
Yang, Fanzhi,Rauch, Karsten,Kettelhoit, Katharina,Ackermann, Lutz
supporting information, p. 11285 - 11288 (2016/02/18)
Versatile ruthenium(II) complexes allow for site-selective C-H oxygenations with weakly-coordinating aldehydes. The challenging C-H functionalizations proceed with high chemoselectivity by rate-determining C-H metalation. The new method features an ample substrate scope, which sets the stage for the step-economical preparation of various bioactive heterocycles.
Synthesis of γ-benzopyranone by TfOH-promoted regioselective cyclization of o-alkynoylphenols
Yoshida, Masahito,Fujino, Yuta,Doi, Takayuki
supporting information; experimental part, p. 4526 - 4529 (2011/10/09)
Regioselective cyclization of o-alkynoylphenols forming γ-benzopyranones has been demonstrated. Trifluoromethanesulfonic acid (TfOH) induced 6-endo cyclization of o-alkynoylphenols without forming 5-exo cyclized benzofuranone derivatives to provide the corresponding γ-benzopyranones in high yields.
Regioselective synthesis of flavone derivatives via DMAP-catalyzed cyclization of o-alkynoylphenols
Yoshida, Masahito,Fujino, Yuta,Saito, Koya,Doi, Takayuki
experimental part, p. 9993 - 9997 (2012/02/06)
A catalytic amount of DMAP promoted cyclization of o-alkynoylphenols via a 6-endo cyclization mode leading to flavone derivatives in high yields without forming 5-exo cyclized aurone derivatives. Utilizing this method, methoxy substituted flavone and alkyl substituted γ-benzopyranone derivatives were synthesized.
