1284813-04-2Relevant academic research and scientific papers
Scalable synthesis of a prostaglandin EP4 receptor antagonist
Gauvreau, Danny,Dolman, Sarah J.,Hughes, Greg,Oshea, Paul D.,Davies, Ian W.
, p. 4078 - 4085 (2010)
The evolution of scalable, economically viable synthetic approaches to the potent and selective prostaglandin EP4 antagonist 1 is presented. The chromatography-free synthesis of multikilogram quantities of 1 using a seven-step sequence (six in the longest
