128483-28-3

Upstream product

• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 17356-08-0 thiourea 
• 128483-24-9 2-(3,4,5-trimethoxybenzylidene)-3,4-dihydronaphthalen-1(2H)-one 

Downstream Products

• 128483-45-4 6-(3,4,5-trimethoxyphenyl)-6H-2,3,7,8-tetrahydrobenzo-1,3-thiazine-<2,3-b>quinazoline-3-one 
• 128483-38-5 2-(p-fluorophenylmethylene)-5-(3,4,5-trimethoxyphenyl)-5H-2,3,6,7-tetrahydrobenzothiazolo<2,3-b>quinazoline-3-one 
• 128483-36-3 2-(3,4,5-trimethoxyphenylmethylene)-5-(3,4,5-trimethoxyphenyl)-5H-2,3,6,7-tetrahydrobenzothiazolo<2,3-b>quinazoline-3-one 
• 128483-41-0 9-Methyl-7-(3,4,5-trimethoxy-phenyl)-5,7-dihydro-6H-10-thia-7a,11-diaza-cyclopenta[b]phenanthren-8-one 
• 128483-37-4 9-[1-(4-Isopropyl-phenyl)-meth-(Z)-ylidene]-7-(3,4,5-trimethoxy-phenyl)-5,7-dihydro-6H-10-thia-7a,11-diaza-cyclopenta[b]phenanthren-8-one 

Relevant academic research and scientific papers

FeCl3·6H2O/TMSBr-catalyzed rapid synthesis of dihydropyrimidinones and dihydropyrimidinethiones under microwave irradiation

An efficient and practical protocol has been developed to synthesize dihydropyrimidinones and dihydropyrimidinethiones through FeCl3 6H2O TMSBr-catalyzed three-component cyclocondensation under microwave irradiation. This approach features high yields, broad substrate scope, short reaction time, mild reaction conditions, operational simplicity and easy work-up, thus affording a versatile method for the synthesis of dihydropyrimidinones and dihydropyrimidinethiones.

SYNTHESIS AND REACTIONS OF 2-MERCAPTO-4-ARYL 4H-1,2,3,4,5,6-HEXAHYDRO-BENZOQUINAZOLINES

2-Mercapto-4-aryl-4H-1,2,3,4,5,6-hexahydrobenzoquinazolines (2), have been synthesized.Compounds 2 reacted with chloroacetic acid, 2-bromopropanoic acid or 3-bromopropanoic acid in the presence of fused sodium acetate and acetic anhydride to give 5-ary