128504-55-2

Upstream product

• 108591-33-9 N-((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-4-methylbenzene sulfonamide 
• 823-45-0 2-(hydroxymethylene)cyclohexanone 
• 492-41-1 (1R,2S)-norephedrine 
• 98-59-9 p-toluenesulfonyl chloride 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 
• 212912-47-5 2RS,4S,5R-4-Methyl-3-p-methylphenylsulphonyl-2-methoxy-5-phenyl-1,3-oxazolidine 
• 670-80-4 4-cyclohexen-1-ylmorpholine 

Relevant academic research and scientific papers

Diastereoselective synthesis of enantiomerically pure 3-organosulfonyl-2-(2-oxocycloalkyl)-1,3-oxazolidines from 2-formylcycloalkanones and β-aminoalkanols

The title compounds (3-arylsulfonyl- or 3-mesyl-2-(2-oxocycloalkyl)-1,3-oxazolidines) belonging to two different diastereomeric series, are prepared selectively by variation of the condensation conditions. By this, the chiral information of the 2-amino-1-

Electrophilic α-formylation of carbonyl compounds using norephedrine-derived 2-metohoxy oxazolidines. A novel asymmetric formation of quaternary stereocenters

The BF3·Et2O promoted addition of enamines and silylenolethers, to the nor-ephedrine-derived orthoamides 1 or 5 has been studied. A judicious choice of the type of nucleophile and electrophile leads to useful selectivities. When a quaternary α-carbonyl stereocenter is created, the direct removal of the chiral auxiliary is possible and renders the overall process an efficient asymmetric carbonyl α-formylation.